Cardiovascular 2009
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Immediate Treatment of TIA or Minor Stroke Reduces Costs and Disability
2/4/2009 OXFORD, England -- Specialty outpatient treatment of transient ischemic attack or minor stroke cut the risk of recurrent stroke and reduced hospital admissions, lengths of stay, costs, and disability, researchers here found.
Panel Supports FDA Approval of Prasugrel
2/4/2009 An FDA advisory committee voted unanimously to recommend that prasugrel (Effient) be approved for preventing thrombosis in high-risk acute coronary syndrome patients after percutaneous coronary intervention.
Wide Variation Found in Radiation Exposure from Cardiac CT Angiography
2/3/200MUNICH -- The median effective radiation dose from cardiac CT angiography is roughly equivalent to that from 600 chest x-rays, researchers said here.
Clinical Benefits Found from Treating Mild Gestational Diabetes
2/3/2009 Treatment of mild gestational diabetes yields some clinical benefit, a randomized trial showed.
Hypertension During Pregnancy Linked to Future Cardiovascular Risk
2/3/2009 Having a hypertensive disorder, including preeclampsia, during pregnancy appears to increase the risk of cardiovascular problems and diabetes in the future, a large, registry-based study showed.
FDA Advisory Panel to Vote on Approval of Prasugrel
2/2/2009 An FDA advisory committee is expected to endorse prasugrel (Effient) for preventing thrombosis in high-risk acute coronary syndrome patients who undergo percutaneous coronary intervention.
Study Finds No Stroke or Mortality Benefit with Off-Pump CABG
1/30/2009 Bypass surgery performed off pump did not reduce the risk of a stroke or lower the postoperative mortality rate, researchers reported here.
Proton Pump Inhibitors Blamed for Clopidogrel Resistance
1/29/2009 Some proton pump inhibitors reduce or eliminate the antiplatelet benefits of clopidogrel (Plavix) and increase the risk of a second heart attack, researchers here found.
Fibrin Peptide Fails Reperfusion Injury Test
1/29/2009 Reperfusion injury was only minimally less when patients received an investigational fibrin derivative during percutaneous coronary intervention following myocardial infarction, according to results of a multinational European trial.
Brief but Intense Exercise May Thwart Diabetes
1/28/2009 As little as three minutes of high-intensity exercise every other day may help sedentary people ward off diabetes, results of a small clinical study suggested.
Youth a Risk Factor for Poor Outcome in Mitral Valve Repair Surgery
1/28/2009 In mitral valve repair surgery, younger patients tend to have a worse outcome, researchers here reported.
BNP Biomarker Called a Poor Guide for Heart Failure Therapy
1/27/2009 Heart failure therapy guided by the cardiac biomarker N-terminal brain natriuretic peptide (BNP) may not improve outcomes, particularly for older patients, researchers found.
FDA to Study Safety of Clopidogrel
1/26/2009 The FDA has announced an investigation into a lack of anti-platelet activity clopidogrel (Plavix) exhibits in some patients.
Heart Association Recommends Daily Intake of Omega-6 Fatty Acids
1/26/2009 At least 5% to 10% of daily caloric intake should come from omega-6 fatty acids, according to an American Heart Association science advisory.
Electronic Health Records with Decision Support Can Save Big Bucks
1/26/2009 Hospitals using electronic health information technologies that help clinicians make patient-care decisions showed better clinical outcomes and reduced costs, researchers here said.
Prolonged Loop Diuretic Use Modestly Boosts Fracture Risk for Women
1/26/2009 Long-term use of loop diuretics may increase fracture risk among postmenopausal women, researchers found.
Cognitive Impairment in Older Persons Linked to Vitamin D Deficiency
1/26/2009 A low level of vitamin D in older patients is associated with a higher risk of cognitive impairment, researchers here said.
Women Physicians Provide Better CHF Treatment
1/21/2009 Women physicians were more likely to follow guidelines and generally deliver better medical care for chronic heart failure patients than male doctors, researchers here reported.
Diastolic Dysfunction Predicts Reduced Exercise Capacity
1/20/2009 Exercise may be good for the heart, but good diastolic function also appears to protect the capacity for exercise, researchers found.
Fewer Cardiac Deaths May Be Attributable to Less Severe First MI
1/20/2009 A decline in first MI severity in recent years may be a factor in the lower rate of mortality from coronary heart disease, researchers here said.
Easy-Going Personality Reduces Dementia Risk
1/19/2009 A relaxed approach to life may protect against dementia in older age regardless of social activity, researchers found.
Cognitive Rehab Helps Patients with Acquired Brain Injuries
1/15/2009 Cognitive rehabilitation can help patients with acquired brain injury, particularly those who have had a stroke, a meta-analysis showed.
Fewer Stents and Better Outcomes Are Hallmarks of Fractional Flow Reserve-Guided PCI
1/14/2009 Measuring fractional flow reserve during percutaneous coronary interventions improved outcomes and reduced the number of drug-eluting stents implanted compared with PCI guided by angiography alone, researchers found.
Women in Cardiac Distress Have More EMS Delays Than Men
1/13/2009 Women with cardiac symptoms are more likely than men to have longer-than-average trips to the hospital, found a study of EMS activity in a major American city.
JUPITER Findings Could Boost Statin Use by 20%
1/13/2009 Roughly 80% of middle-age to older adults could benefit from taking statins, according to researchers here.
Treadmill Exercise and Resistance Training Improve Function in PAD
1/13/2009 Patients with peripheral arterial disease have improved function and circulation with treadmill exercise and leg resistance training, a randomized trial showed.
Morbidly Obese Patients Weigh Heavily on Hospital Finances
1/13/2009 Rising rates of obesity, particularly morbid obesity, are likely to strain hospital resources in coming years, researchers said.
Urinary Excretion Ratio of Sodium to Potassium Predicts Heart-Disease Risk
1/12/2009 The urinary sodium-to-potassium excretion ratio predicts the risk of cardiovascular disease better than sodium or potassium excretion alone, found a retrospective review of two large clinical trials.
Oral Contraceptives Make Gains in Cardiovascular Safety
1/12/2009 Newer generations of hormonal contraceptives may reduce cardiovascular risks compared with early high-dose formulations, researchers said.
A Chill Wind Increases Blood Pressure in Older Age
1/12/2009 Old man winter can boost blood pressure in older patients, French researchers found.
Brain Abnormalities in Dementia Patients Vary by Diabetes Status
1/12/2009 The dementia that has been linked to diabetes is more likely an effect of vascular disease than of Alzheimer's, said researchers here.
Pulse Oximetry May Improve Detection of Congenital Heart Disease in Newborns
1/9/2009 Screening newborns for congenital heart disease using pulse oximetry has high predictive value and a low false-positive rate, a large, prospective study found.
Homocysteine Not Framingham Predicts Cardiovascular Mortality in Very Elderly
1/9/2009 Homocysteine, a biomarker that has a rocky record in cardiovascular disease prevention trials, may prove to be useful as a predictor of cardiovascular mortality in elderly patients, researchers here reported.
FDA Says ENHANCE Results Do Not Shake Cholesterol Theory
1/8/2009 When it comes to cholesterol, lower is still better and lowest may be the best, according to the FDA, which said today that it has completed its review of data from the ENHANCE trial.
Post-Traumatic Stress Linked to Metabolic Syndrome
1/7/2009 Post-traumatic stress disorder can be associated with metabolic syndrome, researchers here found.
Age and Comorbidity No Barrier to Survival Benefit with ICD
1/6/2009 Implantable cardioverter defibrillators reduce mortality in even the oldest, sickest patients, a real-world primary prevention study showed.
Atkins-Style Ketogenic Diet Shines in Blood Sugar Control for Obese Diabetics
1/6/2009 In obese patients with type 2 diabetes, the ketogenic diet -- which stresses high fat and low carbohydrate intake -- outperformed its low-glycemic index rival, researchers found.
Diabetes' Effect on Cognitive Function Spans Age Groups
1/5/2009 Alberta, Jan. 5 -- Cognitive functioning for adults with diabetes begins slowing down early in the disease process and persists for decades, suggested a longitudinal study.
Appropriateness Criteria Offered for Revascularization
1/5/2009 Revascularization is not always indicated in the face of coronary occlusion, although when it is appropriate, bypass surgery is more often the best choice, according to criteria released today.
2/4/2009 OXFORD, England -- Specialty outpatient treatment of transient ischemic attack or minor stroke cut the risk of recurrent stroke and reduced hospital admissions, lengths of stay, costs, and disability, researchers here found.
Panel Supports FDA Approval of Prasugrel
2/4/2009 An FDA advisory committee voted unanimously to recommend that prasugrel (Effient) be approved for preventing thrombosis in high-risk acute coronary syndrome patients after percutaneous coronary intervention.
Wide Variation Found in Radiation Exposure from Cardiac CT Angiography
2/3/200
Clinical Benefits Found from Treating Mild Gestational Diabetes
2/3/2009 Treatment of mild gestational diabetes yields some clinical benefit, a randomized trial showed.
2/3/2009 Having a hypertensive disorder, including preeclampsia, during pregnancy appears to increase the risk of cardiovascular problems and diabetes in the future, a large, registry-based study showed.
FDA Advisory Panel to Vote on Approval of Prasugrel
2/2/2009 An FDA advisory committee is expected to endorse prasugrel (Effient) for preventing thrombosis in high-risk acute coronary syndrome patients who undergo percutaneous coronary intervention.
Study Finds No Stroke or Mortality Benefit with Off-Pump CABG
1/30/2009 Bypass surgery performed off pump did not reduce the risk of a stroke or lower the postoperative mortality rate, researchers reported here.
Proton Pump Inhibitors Blamed for Clopidogrel Resistance
1/29/2009 Some proton pump inhibitors reduce or eliminate the antiplatelet benefits of clopidogrel (Plavix) and increase the risk of a second heart attack, researchers here found.
1/29/2009 Reperfusion injury was only minimally less when patients received an investigational fibrin derivative during percutaneous coronary intervention following myocardial infarction, according to results of a multinational European trial.
Brief but Intense Exercise May Thwart Diabetes
1/28/2009 As little as three minutes of high-intensity exercise every other day may help sedentary people ward off diabetes, results of a small clinical study suggested.
Youth a Risk Factor for Poor Outcome in Mitral Valve Repair Surgery
1/28/2009 In mitral valve repair surgery, younger patients tend to have a worse outcome, researchers here reported.
BNP Biomarker Called a Poor Guide for Heart Failure Therapy
1/27/2009 Heart failure therapy guided by the cardiac biomarker N-terminal brain natriuretic peptide (BNP) may not improve outcomes, particularly for older patients, researchers found.
1/26/2009 The FDA has announced an investigation into a lack of anti-platelet activity clopidogrel (Plavix) exhibits in some patients.
Heart Association Recommends Daily Intake of Omega-6 Fatty Acids
1/26/2009 At least 5% to 10% of daily caloric intake should come from omega-6 fatty acids, according to an American Heart Association science advisory.
Electronic Health Records with Decision Support Can Save Big Bucks
1/26/2009 Hospitals using electronic health information technologies that help clinicians make patient-care decisions showed better clinical outcomes and reduced costs, researchers here said.
Prolonged Loop Diuretic Use Modestly Boosts Fracture Risk for Women
1/26/2009 Long-term use of loop diuretics may increase fracture risk among postmenopausal women, researchers found.
1/26/2009 A low level of vitamin D in older patients is associated with a higher risk of cognitive impairment, researchers here said.
Women Physicians Provide Better CHF Treatment
1/21/2009 Women physicians were more likely to follow guidelines and generally deliver better medical care for chronic heart failure patients than male doctors, researchers here reported.
Diastolic Dysfunction Predicts Reduced Exercise Capacity
1/20/2009 Exercise may be good for the heart, but good diastolic function also appears to protect the capacity for exercise, researchers found.
Fewer Cardiac Deaths May Be Attributable to Less Severe First MI
1/20/2009 A decline in first MI severity in recent years may be a factor in the lower rate of mortality from coronary heart disease, researchers here said.
Easy-Going Personality Reduces Dementia Risk
1/19/2009 A relaxed approach to life may protect against dementia in older age regardless of social activity, researchers found.
Cognitive Rehab Helps Patients with Acquired Brain Injuries
1/15/2009 Cognitive rehabilitation can help patients with acquired brain injury, particularly those who have had a stroke, a meta-analysis showed.
Fewer Stents and Better Outcomes Are Hallmarks of Fractional Flow Reserve-Guided PCI
1/14/2009 Measuring fractional flow reserve during percutaneous coronary interventions improved outcomes and reduced the number of drug-eluting stents implanted compared with PCI guided by angiography alone, researchers found.
Investigational Stent Demonstrates Efficacy in Coronary Bifurcation Lesions
1/14/2009 An investigational self-expanding, drug-eluting stent designed specifically for use in coronary bifurcation lesions demonstrated both safety and efficacy in a multicenter trial, researchers here said.
1/13/2009 Women with cardiac symptoms are more likely than men to have longer-than-average trips to the hospital, found a study of EMS activity in a major American city.
JUPITER Findings Could Boost Statin Use by 20%
1/13/2009 Roughly 80% of middle-age to older adults could benefit from taking statins, according to researchers here.
Treadmill Exercise and Resistance Training Improve Function in PAD
1/13/2009 Patients with peripheral arterial disease have improved function and circulation with treadmill exercise and leg resistance training, a randomized trial showed.
Morbidly Obese Patients Weigh Heavily on Hospital Finances
1/13/2009 Rising rates of obesity, particularly morbid obesity, are likely to strain hospital resources in coming years, researchers said.
Urinary Excretion Ratio of Sodium to Potassium Predicts Heart-Disease Risk
1/12/2009 The urinary sodium-to-potassium excretion ratio predicts the risk of cardiovascular disease better than sodium or potassium excretion alone, found a retrospective review of two large clinical trials.
Oral Contraceptives Make Gains in Cardiovascular Safety
1/12/2009 Newer generations of hormonal contraceptives may reduce cardiovascular risks compared with early high-dose formulations, researchers said.
A Chill Wind Increases Blood Pressure in Older Age
1/12/2009 Old man winter can boost blood pressure in older patients, French researchers found.
Brain Abnormalities in Dementia Patients Vary by Diabetes Status
1/12/2009 The dementia that has been linked to diabetes is more likely an effect of vascular disease than of Alzheimer's, said researchers here.
Pulse Oximetry May Improve Detection of Congenital Heart Disease in Newborns
1/9/2009 Screening newborns for congenital heart disease using pulse oximetry has high predictive value and a low false-positive rate, a large, prospective study found.
Homocysteine Not Framingham Predicts Cardiovascular Mortality in Very Elderly
1/9/2009 Homocysteine, a biomarker that has a rocky record in cardiovascular disease prevention trials, may prove to be useful as a predictor of cardiovascular mortality in elderly patients, researchers here reported.
FDA Says ENHANCE Results Do Not Shake Cholesterol Theory
1/8/2009 When it comes to cholesterol, lower is still better and lowest may be the best, according to the FDA, which said today that it has completed its review of data from the ENHANCE trial.
Post-Traumatic Stress Linked to Metabolic Syndrome
1/7/2009 Post-traumatic stress disorder can be associated with metabolic syndrome, researchers here found.
1/6/2009 Implantable cardioverter defibrillators reduce mortality in even the oldest, sickest patients, a real-world primary prevention study showed.
Atkins-Style Ketogenic Diet Shines in Blood Sugar Control for Obese Diabetics
1/6/2009 In obese patients with type 2 diabetes, the ketogenic diet -- which stresses high fat and low carbohydrate intake -- outperformed its low-glycemic index rival, researchers found.
Diabetes' Effect on Cognitive Function Spans Age Groups
1/5/2009 Alberta, Jan. 5 -- Cognitive functioning for adults with diabetes begins slowing down early in the disease process and persists for decades, suggested a longitudinal study.
Appropriateness Criteria Offered for Revascularization
1/5/2009 Revascularization is not always indicated in the face of coronary occlusion, although when it is appropriate, bypass surgery is more often the best choice, according to criteria released today.
Arousals from Sleep Possible Cause of Apnea in Some Patients
1/5/2009 In patients with heart failure and central sleep apnea, arousals may cause the sleep disorder rather than defending against it, researchers here said.

